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KMID : 0363320170380020164
Journal of Korean Oriental Internal Medicine
2017 Volume.38 No. 2 p.164 ~ p.171
A Case Report of the Efficacy of Saenggan-tang-gagam in the Treatment of a Patient with Chronic Hepatitis B Who Showed Conversion of the Immune-Tolerant Phase to Immune-Clearance Phase during Hospitalization for Intracerebral Hemorrhage
Bae Jung-Han

Kim Ha-Yeon
Joo Seong-Hee
Jang Eun-Gyeong
Lee Jang-Hoon
Kim Young-Chul
Abstract
Objectives: The purpose of this case report is to describe the efficacy of Saenggan-tang-gagam treatment in a patient with immune-tolerant chronic hepatitis B who converted to the immune active phase during hospitalization for Intracerebral hemorrhage.

Methods: A 61-year-old male patient with chronic hepatitis B was hospitalized from July 21, 2016 to October 24, 2016. On September 5, the patient showed fatigue and dyspepsia, and his urine was dark. These symptoms were accompanied by a dramatic elevation of aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP), and gamma-glutamyl transferase (GGT) levels. Saenggan-tang-gagam was administered three times a day until the patient was discharged from the hospital.

Results: After the Saenggan-tang-gagam treatment, AST and ALP levels decreased significantly, below the upper limit level. In addition, the levels of ALT and GG were significantly decreased. In addition, the fatigue, dyspepsia, and dark urine induced by hepatitis improved after the Saenggan-tang-gagam treatment.

Conclusion: This case report suggests that traditional Korean medicine has a beneficial effect on the immune active phase of chronic hepatitis B.
KEYWORD
chronic hepatitis B, immune tolerant phase, immune clearance phase, Saenggan-tang-gagam
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